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Listar por autor "Caballero Velázquez, Teresa"
Mostrando ítems 1-20 de 26
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Artículo
ASXL1 mutation as a surrogate marker in acute myeloid leukemia with myelodysplasia-related changes and normal karyotype
Prats-Martín, Concepción; Burillo-Sanz, Sergio; Morales-Camacho, Rosario M.; Pérez-López, Olga; Suito, Milagros; Vargas de los Monteros, María Teresa; Caballero Velázquez, Teresa; Pérez Simón, José Antonio (Wiley Open Access, 2020)Acute myeloid leukemia with myelodysplasia-related changes (AML-MRC) are poor outcome leukemias. Its diagnosis is based ...
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Artículo
Cannabinoids induce cell death in leukaemic cells through Parthanatos and PARP-related metabolic disruptions
Medrano, M.; Contreras, M.; Caballero Velázquez, Teresa; Martínez, L.; Bejarano-García, J. A.; Calderón Ruiz, Rocío; García-Calderón, C. B.; Valle Rosado, Iván; Pérez Simón, José Antonio (Nature Publishing Group, 2024)BACKGROUND: Several studies have described a potential anti-tumour effect of cannabinoids (CNB). CNB receptor 2 (CB2) is ...
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Artículo
Caspase-8 inhibition represses initial human monocyte activation in septic shock model
Oliva Martín, María José; Sánchez Abarca, Luis Ignacio; Rodhe, Johanna; Carrillo Jiménez, Alejandro; Vlachos, Pinelopi; Herrera Carmona, Antonio José; García Quintanilla, Alberto; Caballero Velázquez, Teresa; Venero Recio, José Luis (Impact Journals, 2016)In septic patients, the onset of septic shock occurs due to the over-activation of monocytes. We tested the therapeutic ...
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Artículo
Combined treatment of graft versus host disease using donor regulatory T cells and ruxolitinib
Rodríguez Gil, Alfonso; Escamilla Gómez, Virginia; Nufer, Melanie; Andújar Sánchez, Félix; Lopes Ramos, Teresa; Bejarano García, José Antonio; Caballero Velázquez, Teresa; Villadiego Luque, Francisco Javier; Pérez Simón, José Antonio (Nature Publishing Group, 2022)Donor derived regulatory T lymphocytes and the JAK1/2 kinase inhibitor ruxolitinib are currently being evaluated as ...
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Artículo
Delayed administration of ixazomib modifies the immune response and prevents chronic graft-versus-host disease
Ramos, Teresa L.; García Guerrero, Estefanía; Caballero Velázquez, Teresa; Rodríguez Gil, Alfonso; Caracuel García, Rocío; Nufer, Melanie; Robles Frías, María José; Barbado González, Mª Victoria; Pérez Simón, José Antonio (Nature Publishing Group, 2021-09-23)In this study, we aimed to modify the immune response in the long term after allogeneic bone marrow transplantation ...
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Artículo
Differential cytogenetic profile in advanced chronic myeloid leukemia with sequential lymphoblastic and myeloblastic blast crisis
Calderón Cabrera, Cristina; Montero, I.; Morales, R. M.; Sánchez, J.; Carrillo, E.; Caballero Velázquez, Teresa; Prats, C.; Bernal, R.; De Blas, J. M.; Pérez Simón, José Antonio (Elsevier, 2013)Frequency of additional chromosomal abnormalities in chronic myeloid leukemia (CML) is estimated to be 7% in chronic phase ...
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Tesis Doctoral
Efecto inmunomodulador de la vitamina D en el periodo postrasplante alogénico de progenitores hematopoyéticos
Montero Cuadrado, María Isabel (2016-01-22)El presente trabajo de tesis se basa en un ensayo clínico multicéntrico realizado a nivel nacional sobre una población de ...
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Artículo
Efficacy of bortezomib to intensify the conditioning regimen and the graft-versus-host disease prophylaxis for high-risk myeloma patients undergoing transplantation
Caballero Velázquez, Teresa; Calderón Cabrera, Cristina; López-Corral, L.; Puig, N.; Marquez-Malaver, F.; Pérez-López, E.; Pérez Simón, José Antonio (Springer Nature, 2020)This multicenter phase I trial was designed to evaluate the safety and efficacy of bortezomib (Bz) as part of both the ...
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Artículo
Evaluation of prognostic factors among patients with chronic graft-versus-host disease
Pérez Simón, José Antonio; Afram, Gabriel; Martino, Rodrigo; Piñana, José L.; Caballero Velázquez, Teresa; Ringden, Olle; Valcárcel, D.; Caballero, Dolores; Remberger, Mats; De Paz, Yanira; Sierra, Jordi; San Miguel, Jesús; Hagglund, Hans (Ferrata-Storti Foundation, 2011)Background: Chronic graft-versus-host disease (cGVHD) is a major complication after allogeneic stem cell transplantation ...
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Artículo
Hematological Neoplasms with Eosinophilia
Morales-Camacho, R.M.; Caballero Velázquez, Teresa; Borrero, J.J.; Bernal, R.; Prats-Martín, C. (MDPI, 2024-01-12)The diagnostic assessment of eosinophilias is complex, requiring a multidisciplinary approach and often involving diagnostic ...
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Artículo
High-Dimensional Analysis of Single-Cell Flow Cytometry Data Predicts Relapse in Childhood Acute Lymphoblastic Leukaemia
Chulián, Salvador; Martínez-Rubio, Álvaro; Pérez-García, Víctor M.; Rosa, María; Blázquez Goñi, Cristina; Rodríguez Gutiérrez, Juan Francisco; Caballero Velázquez, Teresa; Fernández-Martínez, Juan Luis (MDPI, 2021)Artificial intelligence methods may help in unveiling information that is hidden in high-dimensional oncological data. ...
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Artículo
Human Bone Marrow Stromal Cells Differentiate Into Corneal Tissue and Prevent Ocular Graft-Versus-Host Disease in Mice
Sánchez Abarca, Luis Ignacio; Hernández Galilea, Emiliano; Lorenzo, Rebeca; Herrero, Carmen; Verlasco, Almudena; Carrancio, Soraya; Caballero Velázquez, Teresa; Rodríguez Barbosa, José Ignacio; Parrilla, Marta; Del Cañizo, Consuelo; San Miguel, Jesús; Aijón, José; Pérez Simón, José Antonio (SAGE Journals, 2015)Clinical trials have assessed the use of human bone marrow stromal cells (hBMSCs) for the treatment of immune-related ...
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Artículo
Impact of disease burden and late loss of B cell aplasia on the risk of relapse after CD19 chimeric antigen receptor T Cell (Tisagenlecleucel) infusion in pediatric and young adult patients with relapse/refractory acute lymphoblastic leukemia: role of B-cell monitoring
Molinos-Quintana, Águeda; Alonso-Saladrigues, Anna; Herrero, Blanca; Caballero Velázquez, Teresa; Galán-Gómez, Víctor; Panesso, Melissa; Torrebadell, Montserrat; Delgado-Serrano, Javier; Pérez de Soto, Concepción; Pérez Simón, José Antonio (Frontiers Media S.A., 2024-01-16)Introduction: Loss of B-cell aplasia (BCA) is a well-known marker of functional loss of CD19 CAR-T. Most relapses and ...
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Artículo
Monitoring of kinetics and exhaustion markers of circulating CAR-T cells as early predictive factors in patients with B-cell malignancies
García Calderón, Clara Beatriz; Sierro-Martínez, Belén; García-Guerrero, Estefanía; Sanoja-Flores, Luzalba; Muñoz-García, Raquel; Ruiz-Maldonado, Victoria; Carrasco-Brocal, Inmaculada; Pérez Simón, José Antonio; Caballero Velázquez, Teresa (Frontiers Media, 2023)Purpose: CAR-T cell therapy has proven to be a disruptive treatment in the hematology field, however, less than 50% of ...
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Tesis Doctoral
Nuevas estrategias y mecanismos de inmunomodulación en el tratamiento de las hemopatías malignas.
Álvarez Laderas, Isabel (2017-06-19) -
Tesis Doctoral
Nuevas modalidades de inmunoprofilaxis en trasplante: Inhibidores del proteosoma
Calderón Cabrera, Cristina (2017-09-22)El trasplante alogénico de progenitores hematopoyéticos es una opción potencialmente curativa para numerosos pacientes con ...
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Artículo
Phase II Trial of Allogeneic Transplantation Plus Novel Drugs in Multiple Myeloma: Effect of Intensifying Reduced-Intensity Conditioning with Bortezomib and Adding Maintenance Treatment
Reinoso-Segura, Marta; Caballero Velázquez, Teresa; Herrera, Pilar; Patriarca, Francesca; Herrera, Pilar; Fanin, Renato; Bruno, Benedetto; Gahrton, Gösta; Pérez Simón, José Antonio (Elsevier Inc., 2022)The use of reduced-intensity conditioning (RIC) regimens has decreased the risk of nonrelapse mortality (NRM) after ...
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Artículo
Polyphenolic Extract (PE) from Olive Oil Exerts a Potent Immunomodulatory Effect and Prevents Graft-versus-Host Disease in a Mouse Model
Alvarez Laderas, Isabel; Ramos, Teresa L.; Medrano, Mayte; Caracuel García, Rocío; Barbado, María Victoria; Sánchez Hidalgo, Marina; Zamora, Rosario; Alarcón de la Lastra Romero, Catalina; Hidalgo, Francisco J.; Piruat, José Ignacio; Caballero Velázquez, Teresa; Pérez Simón, José Antonio (Elsevier, 2020)Polyphenols are a group of chemical substances found in plants, with immunomodulatory, antiproliferative, and anti-inflammatory ...
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Artículo
Prognostic value of measurable residual disease in patients with AML undergoing HSCT: a multicenter study
Caballero Velázquez, Teresa; Pérez-López, Olga; Yeguas Bermejo, Ana; Rodríguez Arbolí, Eduardo; Colado Varela, Enrique; Sempere Talens, Amparo; Pérez Simón, José Antonio (MDPI, 2023-03-05)Allogeneic hematopoietic stem cell transplantation (HSCT) represents the best therapeutic option for many patients with ...
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Artículo
Reduced intensity conditioning increases risk of severe cGVHD: identification of risk factors for cGVHD in a multicenter setting
Afram, Gabriel; Pérez Simón, José Antonio; Remberger, Mats; Caballero Velázquez, Teresa; Martino, Rodrigo; Piñana, Jose Luis; Ringden, Olle; Esquirol, Albert; Lopez-Corral, Lucia; Hägglund, Hans (Springer, 2018)Chronic graft-versus-host disease (cGVHD) remains a major cause of morbidity and mortality after allogeneic hematopoietic ...